Apical Constriction - Revision history

Neufi03p at 04:06, 26 July 2017

2017-07-26T04:06:36Z

← Older revision		Revision as of 04:06, 26 July 2017
Line 2:		Line 2:
	During embryonic development flat sheets of epithelial cells bend or hinge at specific places at specific times to create important structures like the neural groove and neural folds. Have you ever wondered how a flat sheet of cells does this bending? If you think about it, the box-like cells that make up the flat sheet of an epithelium wouldn’t naturally bend. However, if the surface area of one side of a box became smaller, that box would then become wedge-shaped and a bend would be created in the sheet it is part of. In life this apical constriction is created by a number of different processes, including localized contraction of actinomyosin complexes in the apical border of the cells. You can get a hands-on feel for how this works by joining up a series of boxes and then constricting the apical borders of some of them.		During embryonic development flat sheets of epithelial cells bend or hinge at specific places at specific times to create important structures like the neural groove and neural folds. Have you ever wondered how a flat sheet of cells does this bending? If you think about it, the box-like cells that make up the flat sheet of an epithelium wouldn’t naturally bend. However, if the surface area of one side of a box became smaller, that box would then become wedge-shaped and a bend would be created in the sheet it is part of. In life this apical constriction is created by a number of different processes, including localized contraction of actinomyosin complexes in the apical border of the cells. You can get a hands-on feel for how this works by joining up a series of boxes and then constricting the apical borders of some of them.

	<gallery mode="nolines" widths=~~450px~~ heights=~~400px~~>		<gallery mode="nolines" widths=350px heights=300px>
			ApicalConstriction08.jpeg\|
	ApicalConstriction09.jpeg\|		ApicalConstriction09.jpeg\|
	</gallery>		</gallery>

Neufi03p at 04:04, 26 July 2017

2017-07-26T04:04:11Z

← Older revision		Revision as of 04:04, 26 July 2017
Line 7:		Line 7:

	== Downloadable Files ==		== Downloadable Files ==
	[https://anatomy-teaching-models.wiki.otago.ac.nz/images/5/56/ApicalConstrictionInstructions.pdf ~~Printable Instructions~~]		* [https://anatomy-teaching-models.wiki.otago.ac.nz/images/5/56/ApicalConstrictionInstructions.pdf pdf file of printable instructions]
	[https://anatomy-teaching-models.wiki.otago.ac.nz/images/a/a5/ApicalContrictionPrintOut.pdf pdf of lines to cut and fold]		* [https://anatomy-teaching-models.wiki.otago.ac.nz/images/a/a5/ApicalContrictionPrintOut.pdf pdf file of lines to cut and fold]
			* [https://anatomy-teaching-models.wiki.otago.ac.nz/images/1/17/ApicalContrictionPrintOut.jpg jpg file of lines to cut and fold]

	== Instructions ==		== Instructions ==
	Click to enlarge any of the following images:		Click to enlarge any of the following images:

	1. Print the ~~attached~~ pdf or jpg file onto heavy paper / light cardboard and gather some other gear: scissors, tape, a ruler and some paper clips.		1. Print the downloadable pdf or jpg file onto heavy paper / light cardboard and gather some other gear: scissors, tape, a ruler and some paper clips.
	~~[https://anatomy-teaching-models.wiki.otago.ac.nz/images/a/a5/ApicalContrictionPrintOut.pdf pdf of lines to cut and fold]~~
	<gallery mode="nolines" widths=250px heights=200px>		<gallery mode="nolines" widths=250px heights=200px>
	ApicalConstriction01.jpg\|		ApicalConstriction01.jpg\|

Neufi03p: /* Apical Constriction */

2017-07-26T04:01:49Z

Apical Constriction

← Older revision		Revision as of 04:01, 26 July 2017
Line 3:		Line 3:

	<gallery mode="nolines" widths=450px heights=400px>		<gallery mode="nolines" widths=450px heights=400px>
	ApicalConstriction09.~~jpg~~\|		ApicalConstriction09.jpeg\|
	</gallery>		</gallery>

			== Downloadable Files ==
			[https://anatomy-teaching-models.wiki.otago.ac.nz/images/5/56/ApicalConstrictionInstructions.pdf Printable Instructions]
			[https://anatomy-teaching-models.wiki.otago.ac.nz/images/a/a5/ApicalContrictionPrintOut.pdf pdf of lines to cut and fold]

	== Instructions ==		== Instructions ==
	Click to enlarge any of the following images:		Click to enlarge any of the following images:

	1. Print the attached pdf onto heavy paper / light cardboard and gather some other gear: scissors, tape, a ruler and some paper clips.		1. Print the attached pdf or jpg file onto heavy paper / light cardboard and gather some other gear: scissors, tape, a ruler and some paper clips.
	[https://anatomy-teaching-models.wiki.otago.ac.nz/images/a/a5/ApicalContrictionPrintOut.pdf]		[https://anatomy-teaching-models.wiki.otago.ac.nz/images/a/a5/ApicalContrictionPrintOut.pdf pdf of lines to cut and fold]
	<gallery mode="nolines" widths=250px heights=200px>		<gallery mode="nolines" widths=250px heights=200px>
	ApicalConstriction01.jpg\|		ApicalConstriction01.jpg\|
Line 22:		Line 26:
	3. Use a ruler to fold along the dotted lines. Each of the 7 larger pieces will become a cell.		3. Use a ruler to fold along the dotted lines. Each of the 7 larger pieces will become a cell.
	<gallery mode="nolines" widths=250px heights=200px>		<gallery mode="nolines" widths=250px heights=200px>
	ApicalConstriction03.~~jpg~~\|		ApicalConstriction03.jpeg\|
	</gallery>		</gallery>

	4. Fold the sides of the cells flat and join with tape.		4. Fold the sides of the cells flat and join with tape.
	<gallery mode="nolines" widths=250px heights=200px>		<gallery mode="nolines" widths=250px heights=200px>
	ApicalConstriction04.~~jpg~~\|		ApicalConstriction04.jpeg\|
	</gallery>		</gallery>

	5. Shape the cells back into a box shape. Two of the cells will have four flat faces while the other five will have a couple of extra folds on one face. These extra folds can be flattened out for now.		5. Shape the cells back into a box shape. Two of the cells will have four flat faces while the other five will have a couple of extra folds on one face. These extra folds can be flattened out for now.
	<gallery mode="nolines" widths=250px heights=200px>		<gallery mode="nolines" widths=250px heights=200px>
	ApicalConstriction05.~~jpg~~\|		ApicalConstriction05.jpeg\|
	</gallery>		</gallery>

	6. Join the cells side to side with tape. The two square cells should be at the ends and the remaining cells lined up between them with the extra folds all along the same side.		6. Join the cells side to side with tape. The two square cells should be at the ends and the remaining cells lined up between them with the extra folds all along the same side.
	<gallery mode="nolines" widths=250px heights=200px>		<gallery mode="nolines" widths=250px heights=200px>
	ApicalConstriction06.~~jpg~~\|		ApicalConstriction06.jpeg\|
	</gallery>		</gallery>

	7. Tape the two remaining squares of paper to the end cells so they keep their square profile.		7. Tape the two remaining squares of paper to the end cells so they keep their square profile.
	<gallery mode="nolines" widths=250px heights=200px>		<gallery mode="nolines" widths=250px heights=200px>
	ApicalConstriction07.~~jpg~~\|		ApicalConstriction07.jpeg\|
	</gallery>		</gallery>

	8. The completed flat row of cuboidal cells.		8. The completed flat row of cuboidal cells.
	<gallery mode="nolines" widths=250px heights=200px>		<gallery mode="nolines" widths=250px heights=200px>
	ApicalConstriction08.~~jpg~~\|		ApicalConstriction08.jpeg\|
	</gallery>		</gallery>

	9. Now constrict the apical portions of the five middle cells to see how the curve is created. Hold in place with paper clips.		9. Now constrict the apical portions of the five middle cells to see how the curve is created. Hold in place with paper clips.
	<gallery mode="nolines" widths=250px heights=200px>		<gallery mode="nolines" widths=250px heights=200px>
	ApicalConstriction09.~~jpg~~\|		ApicalConstriction09.jpeg\|
	</gallery>		</gallery>

Marro19p at 03:21, 26 July 2017

2017-07-26T03:21:24Z

← Older revision		Revision as of 03:21, 26 July 2017
Line 10:		Line 10:

	1. Print the attached pdf onto heavy paper / light cardboard and gather some other gear: scissors, tape, a ruler and some paper clips.		1. Print the attached pdf onto heavy paper / light cardboard and gather some other gear: scissors, tape, a ruler and some paper clips.
	[https://anatomy-teaching-models.wiki.otago.ac.nz/images/1/11/ApicalContrictionPrintOut.pdf]		[https://anatomy-teaching-models.wiki.otago.ac.nz/images/a/a5/ApicalContrictionPrintOut.pdf]
	<gallery mode="nolines" widths=250px heights=200px>		<gallery mode="nolines" widths=250px heights=200px>
	ApicalConstriction01.jpg\|		ApicalConstriction01.jpg\|

Neufi03p at 02:56, 25 July 2017

2017-07-25T02:56:23Z

← Older revision		Revision as of 02:56, 25 July 2017
Line 3:		Line 3:

	<gallery mode="nolines" widths=450px heights=400px>		<gallery mode="nolines" widths=450px heights=400px>
	ApicalConstriction09.jpg\|		ApicalConstriction09.jpg\|
	</gallery>		</gallery>

Line 10:		Line 10:

	1. Print the attached pdf onto heavy paper / light cardboard and gather some other gear: scissors, tape, a ruler and some paper clips.		1. Print the attached pdf onto heavy paper / light cardboard and gather some other gear: scissors, tape, a ruler and some paper clips.
			[https://anatomy-teaching-models.wiki.otago.ac.nz/images/1/11/ApicalContrictionPrintOut.pdf]
	<gallery mode="nolines" widths=250px heights=200px>		<gallery mode="nolines" widths=250px heights=200px>
	ApicalConstriction01.jpg\|		ApicalConstriction01.jpg\|
Line 21:		Line 22:
	3. Use a ruler to fold along the dotted lines. Each of the 7 larger pieces will become a cell.		3. Use a ruler to fold along the dotted lines. Each of the 7 larger pieces will become a cell.
	<gallery mode="nolines" widths=250px heights=200px>		<gallery mode="nolines" widths=250px heights=200px>
	ApicalConstriction03.jpg\|		ApicalConstriction03.jpg\|
	</gallery>		</gallery>

	4. Fold the sides of the cells flat and join with tape.		4. Fold the sides of the cells flat and join with tape.
	<gallery mode="nolines" widths=250px heights=200px>		<gallery mode="nolines" widths=250px heights=200px>
	ApicalConstriction04.jpg\|		ApicalConstriction04.jpg\|
	</gallery>		</gallery>

	5. Shape the cells back into a box shape. Two of the cells will have four flat faces while the other five will have a couple of extra folds on one face. These extra folds can be flattened out for now.		5. Shape the cells back into a box shape. Two of the cells will have four flat faces while the other five will have a couple of extra folds on one face. These extra folds can be flattened out for now.
	<gallery mode="nolines" widths=250px heights=200px>		<gallery mode="nolines" widths=250px heights=200px>
	ApicalConstriction05.jpg\|		ApicalConstriction05.jpg\|
	</gallery>		</gallery>

	6. Join the cells side to side with tape. The two square cells should be at the ends and the remaining cells lined up between them with the extra folds all along the same side.		6. Join the cells side to side with tape. The two square cells should be at the ends and the remaining cells lined up between them with the extra folds all along the same side.
	<gallery mode="nolines" widths=250px heights=200px>		<gallery mode="nolines" widths=250px heights=200px>
	ApicalConstriction06.jpg\|		ApicalConstriction06.jpg\|
	</gallery>		</gallery>

	7. Tape the two remaining squares of paper to the end cells so they keep their square profile.		7. Tape the two remaining squares of paper to the end cells so they keep their square profile.
	<gallery mode="nolines" widths=250px heights=200px>		<gallery mode="nolines" widths=250px heights=200px>
	ApicalConstriction07.jpg\|		ApicalConstriction07.jpg\|
	</gallery>		</gallery>

	8. The completed flat row of cuboidal cells.		8. The completed flat row of cuboidal cells.
	<gallery mode="nolines" widths=250px heights=200px>		<gallery mode="nolines" widths=250px heights=200px>
	ApicalConstriction08.jpg\|		ApicalConstriction08.jpg\|
	</gallery>		</gallery>

	9. Now constrict the apical portions of the five middle cells to see how the curve is created. Hold in place with paper clips.		9. Now constrict the apical portions of the five middle cells to see how the curve is created. Hold in place with paper clips.
	<gallery mode="nolines" widths=250px heights=200px>		<gallery mode="nolines" widths=250px heights=200px>
	ApicalConstriction09.jpg\|		ApicalConstriction09.jpg\|
	</gallery>		</gallery>

Neufi03p at 02:51, 25 July 2017

2017-07-25T02:51:09Z

← Older revision		Revision as of 02:51, 25 July 2017
Line 2:		Line 2:
	During embryonic development flat sheets of epithelial cells bend or hinge at specific places at specific times to create important structures like the neural groove and neural folds. Have you ever wondered how a flat sheet of cells does this bending? If you think about it, the box-like cells that make up the flat sheet of an epithelium wouldn’t naturally bend. However, if the surface area of one side of a box became smaller, that box would then become wedge-shaped and a bend would be created in the sheet it is part of. In life this apical constriction is created by a number of different processes, including localized contraction of actinomyosin complexes in the apical border of the cells. You can get a hands-on feel for how this works by joining up a series of boxes and then constricting the apical borders of some of them.		During embryonic development flat sheets of epithelial cells bend or hinge at specific places at specific times to create important structures like the neural groove and neural folds. Have you ever wondered how a flat sheet of cells does this bending? If you think about it, the box-like cells that make up the flat sheet of an epithelium wouldn’t naturally bend. However, if the surface area of one side of a box became smaller, that box would then become wedge-shaped and a bend would be created in the sheet it is part of. In life this apical constriction is created by a number of different processes, including localized contraction of actinomyosin complexes in the apical border of the cells. You can get a hands-on feel for how this works by joining up a series of boxes and then constricting the apical borders of some of them.

	<gallery mode="nolines" widths=~~250px~~ heights=~~200px~~>		<gallery mode="nolines" widths=450px heights=400px>
	ApicalConstriction09.jpg\|		ApicalConstriction09.jpg\|
	</gallery>		</gallery>
Line 14:		Line 14:
	</gallery>		</gallery>

	2. Cut along all the solid lines		2. Cut along all the solid lines.
	<gallery mode="nolines" widths=250px heights=200px>		<gallery mode="nolines" widths=250px heights=200px>
	ApicalConstriction02.jpg\|		ApicalConstriction02.jpg\|

Neufi03p: Created page with "=Apical Constriction= During embryonic development flat sheets of epithelial cells bend or hinge at specific places at specific times to create important structures like the n..."

2017-07-25T02:46:24Z

Created page with "=Apical Constriction= During embryonic development flat sheets of epithelial cells bend or hinge at specific places at specific times to create important structures like the n..."

New page

=Apical Constriction=
During embryonic development flat sheets of epithelial cells bend or hinge at specific places at specific times to create important structures like the neural groove and neural folds. Have you ever wondered how a flat sheet of cells does this bending? If you think about it, the box-like cells that make up the flat sheet of an epithelium wouldn’t naturally bend. However, if the surface area of one side of a box became smaller, that box would then become wedge-shaped and a bend would be created in the sheet it is part of. In life this apical constriction is created by a number of different processes, including localized contraction of actinomyosin complexes in the apical border of the cells. You can get a hands-on feel for how this works by joining up a series of boxes and then constricting the apical borders of some of them.

<gallery mode="nolines" widths=250px heights=200px>
ApicalConstriction09.jpg|
</gallery>

== Instructions ==
Click to enlarge any of the following images:

1. Print the attached pdf onto heavy paper / light cardboard and gather some other gear: scissors, tape, a ruler and some paper clips.
<gallery mode="nolines" widths=250px heights=200px>
ApicalConstriction01.jpg|
</gallery>

2. Cut along all the solid lines
<gallery mode="nolines" widths=250px heights=200px>
ApicalConstriction02.jpg|
</gallery>

3. Use a ruler to fold along the dotted lines. Each of the 7 larger pieces will become a cell.
<gallery mode="nolines" widths=250px heights=200px>
ApicalConstriction03.jpg|
</gallery>

4. Fold the sides of the cells flat and join with tape.
<gallery mode="nolines" widths=250px heights=200px>
ApicalConstriction04.jpg|
</gallery>

5. Shape the cells back into a box shape. Two of the cells will have four flat faces while the other five will have a couple of extra folds on one face. These extra folds can be flattened out for now.
<gallery mode="nolines" widths=250px heights=200px>
ApicalConstriction05.jpg|
</gallery>

6. Join the cells side to side with tape. The two square cells should be at the ends and the remaining cells lined up between them with the extra folds all along the same side.
<gallery mode="nolines" widths=250px heights=200px>
ApicalConstriction06.jpg|
</gallery>

7. Tape the two remaining squares of paper to the end cells so they keep their square profile.
<gallery mode="nolines" widths=250px heights=200px>
ApicalConstriction07.jpg|
</gallery>

8. The completed flat row of cuboidal cells.
<gallery mode="nolines" widths=250px heights=200px>
ApicalConstriction08.jpg|
</gallery>

9. Now constrict the apical portions of the five middle cells to see how the curve is created. Hold in place with paper clips.
<gallery mode="nolines" widths=250px heights=200px>
ApicalConstriction09.jpg|
</gallery>

'''Creators:''' Fieke Neuman and Dr Christine Jasoni. Both from [http://www.otago.ac.nz/anatomy Department of Anatomy], [http://www.otago.ac.nz University of Otago]

'''Keywords:''' Teaching, Anatomy, Development, Science, Biology

[[Image:CC.png|link=http://creativecommons.org/licenses/by-nc-sa/4.0/]]

This work is licensed under a [http://creativecommons.org/licenses/by-nc-sa/4.0/ Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License]